If you have anaphylaxis, an AAI pen is a VITAL tool that you must never be without.  

Allergy UK’s Head of Clinical Services Margaret Kelman, shares her AAI 101 to ensure you’re not caught out in an emergency situation and you stay safe. 

1. MAKE SURE YOUR AAI IS IN DATE! AAI pens all have an expiry date. Check to make sure yours is in date, and if it isn’t, get that prescription in quick.  Don’t discard your expired AAI until you receive your in date one though. In an emergency, an expired AAI is better than none at all. You can set up an expiry date reminder with your AAI provider here

2. CHECK THAT THE ADRENALINE IS STABLE. Even if an AAI is in date, sometimes how you store it can result in the adrenaline deteriorating. AAI’s should be kept at room temperature and away from direct sunlight and extreme temperatures. Although they are quite robust devices they should not be exposed to extreme temperatures such as the fridge or glove compartments of cars.  You can check if your AAI is safe to use through the inspection window on the device:

  • If the solution is clear/colourless, it is safe to use.
  • If the solution is discoloured or contains particles, you will need to replace it, even if this occurs before the expiry date. However, do not discard your old AAI until you have a replacement.


 4.KNOW HOW TO USE YOUR AAI AND MAKE SURE YOU and any carers know when and how to use your auto-injector. These videos from Allergy UK show you how to use a JEXT AAI and an EPI PEN AAI. You should also read the leaflet that comes with the AAI and can even practice with a training device, which you can get from the manufacturer.

 5. IF IN DOUBT, USE YOUR AAI. In the event of a suspected anaphylactic reaction, it is much better to use adrenaline early than to delay treatment until you’re sure you’re experiencing severe anaphylaxis.  There are no known negative impacts to your health if you use an AAI pen when it’s not necessary, but remember: if you require adrenaline for an allergic reaction you will need to be assessed in hospital even if you start to feel better.

Anaphylaxis symptoms and action sheet

Anaphylaxis symptoms and action sheet

Our Anaphylaxis Symptoms and Action Sheet is your essential resource for recognising the signs of anaphylaxis and knowing how to respond swiftly and effectively in case of an emergency. Download your copy today and empower yourself with life-saving knowledge.

Adrenaline auto-injectors

Adrenaline auto-injectors

This information factsheet has been developed to highlight the importance of carrying your adrenaline auto-injectors. It will also cover the different types and brands of adrenaline auto injectors available in the UK as well as how to care for your adrenaline auto injector.

Allergy Insights Podcast: Anaphylaxis and AAI's

Allergy Insights Podcast: Anaphylaxis and AAI's

We’ve recorded a new episode of our ‘Allergy Insights’ podcast that provides expert advice on anaphylactic reactions and the use of adrenaline to support patients and carers of those at risk of anaphylaxis. Amena Warner, Head of Clinical at Allergy UK, joined by Professor Adam Fox, a leading allergy expert, to discuss the importance of early recognition and treatment of anaphylaxis.

ALK has provided a financial contribution to the production of this digital destination but has had no editorial input into the design, content or other outputs.

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